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EUROPEAN MEETING ON MOLECULAR DIAGNOSTICS
October 22nd & 23rd, 2009 in the Kurhaus Hotel, Scheveningen,
The Netherlands
Thursday October 22nd 2009
Session 1: TECHNICAL AND CLINICAL DEVELOPMENTS IN MOLECULAR DIAGNOSTICS
Chair: Dr. Winand Dinjens & Dr. Adriaan van den Brule
Molecular markers for Personalized Oncology Diagnosis and Treatment
Dr. David Sidransky
Director of Otolaryngology, HNCR Division at Johns Hopkins University, Baltimore USA
Quantitative multiplex pathogen detection using proximity dependent DNA ligation
Cor Schoen*, Odette Mendes, Rachel Nong, Spyros Darmanis, Ulf Landegren
Plant Research International, Wageningen UR, Wageningen, The Netherlands
Dept of Genetics and Pathology/Molecular Medicine, Uppsala University , Rudbeck Laboratory, Uppsala, Sweden
A novel flexible system for High Throughput DNA-testing of human genetic variation
W.A. van Haeringen*, L.H.P. van de Goor, M.P. Van de Vegte
Mocite B.V., Wageningen, The Netherlands
Geneticom B.V., Rijswijk, The Netherlands
Session 2: MOLECULAR DIAGNOSTICS IN PATHOLOGY
Chair: Dr. David Sidransky & Dr. Oliver Stoss
Biomarker development: challenges and opportunities
Dr. David Sidransky
Director of Otolaryngology, HNCR Division at Johns Hopkins University, Baltimore USA
Clinical importance of Her2/neu molecular testing in esophageal and stomach cancers
Dr. Oliver Stoss
Targos Molecular Pathology,Kassel, Germany
KRAS mutation detection and prognostic potential in sporadic colorectal cancer using high resolution melting analysis
Marc Baay*, Vanessa Deschoolmeester, Carolien Boeckx, Eric Van Marck, Wim Wuyts, Peter Vermeulen, Filip Lardon, Jan B. Vermorken
Laboratory of Cancer Research and Clinical Oncology, Department of Medical Oncology, University of Antwerp (UA/UZA), Wilrijk, Belgium
Department of Pathology and Department of Medical Genetics, University of Antwerp(UA/UZA), Wilrijk, Belgium
Translational Cancer Research Group, Oncology Center, General Hospital St Augustinus, Wilrijk, Belgium
MammaPrint and TargetPrint microarray diagnostics of breast cancer: joint distribution, stability and reproducibility
Paul Roepman*, Leonie Delahaye, Oscar Krijgsman, Annuska Glas
Agendia BV, Amsterdam, the Netherlands
Cross-reactivity of the hybrid capture with untargeted human Papillomavirus genotypes and their relationship with the phylogenetical grouping
Rodríguez-Iglesias MA*, Galán-Sánchez F, Román-Enri M, García-Valdivia MS
Microbiology Lab, Puerto Real Univ Hosp, Spain
Comparison of the clinical performance of the PapilloCheck HPV detection with GP5+/6+-PCR in population-based cervical screening
A.T. Hesselink*, D.A.M. Heideman, J. Berkhof, F. Topal, R.P. Pol, C.J.L.M. Meijer, P.J.F. Snijders
Department of Pathology VU University medical center, Amsterdam, the Netherlands
Department of Epidemiology and Biostatistics VU University medical center, Amsterdam, the Netherlands
Session 3: MOLECULAR DIAGNOSTICS IN VIROLOGY
Chair: Dr. Kate Templeton & Dr. Rob Schuurman
New Developments in Clinical Molecular Virology
Dr. Kate Templeton
Royal Infirmary Edinburgh, UK
Development of a real-time RT-PCR for the detection of Swine-lineage Influenza A (H1N1) virus infections
Michael J. Carr*, Rory Gunson, Alasdair Maclean, Suzie Coughlan, Jeff Connell, William F. Carman, William W. Hall
National Virus Reference Laboratory, University College Dublin, Ireland
West of Scotland Specialist Virology Centre, Gartnavel General Hospital, Glasgow, United Kingdom
Molecular epidemiology of tick-borne encephalitis viruses in Switzerland: Establishment of a sample preparation and real-time RT-PCR protocol
Gäumann Rahel*, Mühlemann Kathrin, Beuret Christian
Institute for Infectious Diseases University of Berne, Switzerland
Spiez Laboratory Federal Office for Civil Protection, Spiez, Switzerland
Measuring Human Immunodeficiency Virus Type 1 RNA Loads in Dried Blood Spots Specimens using NucliSENS EasyQ HIV-1 v2.0
Peter van Deursen*, Tom Oosterlaken, Patrice Andre, André Verhoeven, Veronique Ligeon, Jacques de Jong
bioMérieux bv, Boxtel, The Netherlands
Hôpital de la Croix-Rousse, Lyon, France
bioMérieux SA, centre Christophe Mérieux, Grenoble, France
Evaluation of an affordable Assay for Drug-Resistance Genotyping of All Major HIV-1 Subtypes
Susan C. Aitken*, Aletta Kliphuis, Carole L. Wallis, Mei Ling Chu, Wendy Stevens, Tobias F. Rinke de Wit, Rob Schuurman
University of the Witwatersrand, Johannesburg, South Africa
University Medical Centre, Utrecht, The Netherlands
Center for Poverty-related Communicable Diseases (CPCD), PharmAccess Foundation, Academic Medical Center, Amsterdam, The Netherlands
POSTER SESSION PLUS INFORMAL GATHERING
Conference dinner on the Pier 19.00
Friday October 23rd 2009
Session 4: MOLECULAR DIAGNOSTICS IN COMPANIES FUTURE VISION
Vision and Strategy in Molecular Diagnostics at Abbott Molecular
Abbott Molecular Inc., Mr. John Robinson
Life Technologies Molecular Diagnostics, Present and Future
Life Technologies, Mrs. Kim Cable
Innovative New Developments for Routine Molecular Diagnostics
Qiagen GmbH, Dr. Mario Fangareggi
Molecular diagnostics in Roche’s future vision
Roche Diagnostics, Mr. C.A. Brown
Session 5: MOLECULAR DIAGNOSTICS IN CLINICAL GENETICS
Chair: Ron van Schaik, PhD & Dr. Kristel Sleegers
Pharmacogenetics, from bench to bedside
Ron van Schaik, PhD.
Dept. Clinical Chemistry (AKC) Erasmus Medical Centre, Rotterdam, The Netherlands
Molecular Genetics of Alzheimer’s Disease
Dr. Kristel Sleegers
Neurodegenerative Brain Diseases group, Department of Molecular Genetics, VIB
Laboratory of Neurogenetics, Institute Born-Bunge
University of Antwerp, Belgium
High Resolution Melting analysis for genotyping Gilbert’s Syndrome marker UGT1A1*28
Freya Vaeyens*, Els Bailleul, Peter Meeus, Anne Vankeerberghen, Hans De Beenhouwer
Molecular Laboratory, Onze Lieve Vrouw Ziekenhuis Aalst, Belgium
Patients with partial resistance to acenocoumarol and phenprocoumon; screening the VKORC1 gene
J. Poodt*, P.C.J. Schmeits, J.H.H. Van Geest-Daalderop, J.M.H. Conemans, M.H.A. Hermans
Jeroen Bosch Hospital Molecular Diagnostics, ‘s-Hertogenbosch, The Netherlands
Laboratory of Pharmacology and Toxicology Hospital Pharmacy Noordoost-Brabant, ‘s-Hertogenbosch, The Netherlands
Thrombosis Service Department of Laboratory of Clinical Chemistry and Haematology Jeroen Bosch Hospital, ‘s-Hertogenbosch, The Netherlands
Session 6: INNOVATIVE SEQUENCING TECHNOLOGIES
Chair: Dr. Sarah Palmer & Dr. Simon Harris
Applications of Sequencing Technologies in Virology
Dr. Sarah Palmer
Dept. of Virology, Karolinska Institute Stockholm, Sweden
High Throughput sequencing shows hospital transmission and intercontinental spread in MRSA ST239
Dr. Simon Harris
The Wellcome Trust Sanger Institute, Hinxton Cambridge, UK
Session 7: MOLECULAR DIAGNOSTICS IN CLINICAL MICROBIOLOGY
Chair: Dr. Laurent Poirel & Dr. Alex van Belkum
Molecular Diagnostics and Epidemiology of Beta-Lactamases
Dr. Laurent Poirel
Dept. of Microbiology, Hôpital de Bicêtre, Le Kremlin Bicêtre, France
Evaluation of Malditof-MS for identification of clinically important bacteria not identified by phenotypic assays & Malditof MS identification direct from blood culture bottles
C.H.E. Boel*, W.P. Engel, A.M. Terlingen, A.C. Fluit
Dept. of Medical Microbiology, University Medical Center Utrecht, the Netherlands
Experience with molecular methods and culture in detection of staphylococci in surgically treated patients with infective endocarditis
Žaloudíková B.*, Nìmcová E., Vanìrková M., Pol J., Šorm Z., Wurmová Š., Novotná K., Nìmec P.
Centre for Cardiovascular Surgery and Transplantation, Molecular Genetics Laboratory, Brno, Czech Republic
Institute of Clinical and Experimental Medicine, Prague, Czech Republic
Cardiovascular Surgery Clinic, Charles University Hospital, Hradec Králové, Czech Republic
Real-time PCR is indispensable for early diagnosis of acute Q-fever
Jeroen Schellekens, Peter Wever, Peter Schneeberger, Erik van Hannen, Sander Leenders, Mirjam Hermans*
Molecular Diagnostics Jeroen Bosch Hospital, ’s-Hertogenbosch, The Netherlands
Department of Medical Microbiology and Infection Control Jeroen Bosch Hospital, 's-Hertogenbosch, The Netherlands
Department of Medical Microbiology and Immunology St. Antonius Hospital, Nieuwegein, The Netherlands
A DNA micro-array for rapid detection of TEM, SHV and CTX-M extended spectrum beta-lactamases (ESBLs): comparison with phenotypic confirmatory methods
R.H.T. Nijhuis*, R. Bosboom, A. van Griethuysen, B. Postma, A.A. van Zwet
Department of Clinical Microbiology and Immunology Alysis Zorggroep, Velp, The Netherlands
Department of Clinical Microbiology Slingeland Hospital, Doetinchem, The Netherlands
Department of Clinical Microbiology Hospital Gelderse Vallei, Ede, The Netherlands
Closure of the Meeting and final remarks
End of Meeting on Molecular Diagnostics |
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